Roger Schibli Selected Research

1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid

1/2022	Combination of terbium-161 with somatostatin receptor antagonists-a potential paradigm shift for the treatment of neuroendocrine neoplasms.
1/2022	Design and Evaluation of Novel Albumin-Binding Folate Radioconjugates: Systematic Approach of Varying the Linker Entities.
1/2021	Promising potential of [177Lu]Lu-DOTA-folate to enhance tumor response to immunotherapy-a preclinical study using a syngeneic breast cancer model.
1/2020	Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [177Lu]Lu-PP-F11N.
12/2017	44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617-preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617.
1/2017	Evaluation of the first 44Sc-labeled Affibody molecule for imaging of HER2-expressing tumors.
2/2016	ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo.
3/2014	Folate receptor targeted alpha-therapy using terbium-149.
1/2013	DOTA conjugate with an albumin-binding entity enables the first folic acid-targeted 177Lu-radionuclide tumor therapy in mice.
1/2013	DOTA-functionalized polylysine: a high number of DOTA chelates positively influences the biodistribution of enzymatic conjugated anti-tumor antibody chCE7agl.

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Roger Schibli Research Topics

Disease

123	Neoplasms (Cancer) 01/2022 - 05/2006
13	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 10/2013
11	Carcinoma (Carcinomatosis) 09/2018 - 01/2005
9	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 04/2008
7	Neoplasm Metastasis (Metastasis) 10/2022 - 11/2010
7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 09/2013
7	Atherosclerotic Plaque (Atheroma) 04/2017 - 01/2013
5	Inflammation (Inflammations) 11/2018 - 11/2010
4	Breast Neoplasms (Breast Cancer) 10/2022 - 08/2014
4	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 09/2013
4	Neuroendocrine Tumors (Neuroendocrine Tumor) 05/2019 - 09/2013
4	Insulinoma 05/2019 - 04/2017
4	Neuroinflammatory Diseases 01/2019 - 03/2015
4	Infections 01/2017 - 12/2015
4	Autoimmune Diseases (Autoimmune Disease) 01/2014 - 02/2008
3	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 03/2014
3	Interstitial Lung Diseases (Interstitial Lung Disease) 09/2020 - 01/2019
3	Fibrosis (Cirrhosis) 01/2019 - 01/2018
3	Atherosclerosis 04/2017 - 01/2013
3	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 11/2014 - 12/2008
3	Rupture 08/2014 - 06/2013
2	Thyroid Neoplasms (Thyroid Cancer) 01/2020 - 01/2016
2	Cognitive Dysfunction 01/2020 - 04/2015
2	Nervous System Diseases (Neurological Disorders) 11/2019 - 06/2019
2	Hypoglycemia (Reactive Hypoglycemia) 01/2019 - 12/2013
2	Lung Injury 11/2018 - 01/2018
2	Pneumonia (Pneumonitis) 11/2018 - 02/2016

Drug/Important Bio-Agent (IBA)

49	Folic Acid (Vitamin M)FDA LinkGeneric 01/2022 - 05/2006
25	Radioisotopes (Radionuclides)IBA 04/2021 - 08/2007
18	AlbuminsIBA 01/2022 - 12/2010
14	Peptides (Polypeptides)IBA 01/2022 - 12/2008
12	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 01/2022 - 07/2011
11	RadiopharmaceuticalsIBA 12/2020 - 10/2006
10	AcidsIBA 01/2020 - 07/2006
9	LigandsIBA 01/2022 - 02/2015
9	minigastrinIBA 12/2021 - 05/2014
8	AntigensIBA 01/2020 - 12/2017
8	Pemetrexed (MTA)FDA Link 01/2018 - 12/2006
7	Biological ProductsIBA 12/2020 - 01/2013
7	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2010
7	BombesinIBA 03/2015 - 12/2008
6	Cholecystokinin B ReceptorIBA 05/2021 - 05/2014
6	Bombesin Receptors (Bombesin Receptor)IBA 03/2015 - 12/2008
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2010
5	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 12/2008
5	Monoclonal AntibodiesIBA 01/2017 - 02/2010
5	Tyrosine (L-Tyrosine)FDA Link 01/2016 - 07/2009
5	Folic Acid AntagonistsIBA 04/2010 - 12/2006
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022 - 06/2019
4	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2022 - 09/2013
4	Lutetium-177IBA 01/2021 - 10/2014
4	Blood Proteins (Serum Proteins)IBA 05/2020 - 01/2013
4	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 01/2020 - 07/2009
4	Pharmaceutical PreparationsIBA 11/2019 - 08/2007
4	177Lu-PSMA-617IBA 08/2019 - 01/2018
4	Cannabinoid Receptors (Cannabinoid Receptor)IBA 02/2018 - 03/2014
4	Tryptophan (L-Tryptophan)FDA Link 01/2016 - 03/2012
4	CB2 Cannabinoid ReceptorIBA 01/2016 - 09/2013
4	Amino Acids FDA Link 01/2016 - 03/2012
3	Chelating AgentsIBA 01/2022 - 04/2009
3	Terbium-161IBA 01/2022 - 10/2014
3	Edotreotide (SMT 487)IBA 01/2022 - 05/2017
3	TerbiumIBA 01/2022 - 12/2012
3	PeptidomimeticsIBA 05/2021 - 01/2020
3	Peptide Hydrolases (Proteases)FDA Link 05/2021 - 01/2015
3	AmidesIBA 05/2021 - 01/2020
3	TriazolesIBA 04/2021 - 12/2008
3	SolutionsIBA 01/2020 - 01/2017
3	Peptide Receptors (Peptide Receptor)IBA 01/2020 - 12/2008
3	gallium 68 PSMA-11IBA 07/2019 - 12/2017
3	Exenatide (Byetta)FDA Link 05/2019 - 01/2018
3	1- (1,3- carboxypropyl)- 4,7- carboxymethyl- 1,4,7- triazacyclononaneIBA 01/2019 - 01/2016
3	(18F)fluoroethyltyrosineIBA 01/2016 - 01/2013
3	Indicators and Reagents (Reagents)IBA 01/2016 - 11/2010
3	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 12/2015 - 04/2008
3	ThymidineIBA 03/2013 - 06/2009
3	Immunoconjugates (Immunoconjugate)IBA 01/2013 - 06/2012
2	CannabinoidsIBA 10/2022 - 09/2013
2	Ibuprofen (Motrin)FDA LinkGeneric 01/2022 - 01/2020
2	Mechanistic Target of Rapamycin Complex 1IBA 12/2021 - 01/2020
2	Everolimus FDA Link 12/2021 - 01/2020
2	IsotopesIBA 04/2021 - 01/2020
2	Therapeutic UsesIBA 01/2021 - 11/2012
2	Phosphotransferases (Kinase)IBA 01/2020 - 01/2016
2	Fluorine-18IBA 01/2020 - 01/2013
2	Amyloid (Amyloid Fibrils)IBA 01/2020 - 04/2015
2	Protons (Proton)IBA 09/2019 - 10/2007
2	PSMA-617IBA 07/2019 - 12/2017
2	LipopolysaccharidesIBA 01/2019 - 03/2015
2	SiliconIBA 01/2018 - 10/2013
2	Metabotropic Glutamate 5 ReceptorIBA 01/2018 - 05/2015
2	Insulin (Novolin)FDA Link 04/2017 - 12/2013
2	Apolipoproteins E (ApoE)IBA 04/2017 - 12/2016
2	ApolipoproteinsIBA 04/2017 - 04/2015

Therapy/Procedure

53	Therapeutics 01/2022 - 08/2007
6	Castration 01/2021 - 01/2018
5	Radioimmunotherapy 09/2018 - 11/2012
4	Radiotherapy 09/2019 - 04/2008
2	Immunotherapy 01/2021 - 01/2011
2	Injections 01/2020 - 01/2013